| Day | Date | Opponent | Location | Outcome/Time |
| Sat | 02/10/2001 | TROY STATE (DH) | Birmingham, Ala. | L, 1-0
Recap | Stats |
| Sat | 02/10/2001 | TROY STATE | Birmingham, Ala. | L, 3-1
Stats |
| Thu | 02/15/2001 | Georgia (DH) | Athens, Ga. | L, 1-0
Recap | Stats |
| Thu | 02/15/2001 | Georgia | Athens, Ga. | W, 5-1
Recap | Stats |
| Fri | 02/16/2001 | Marshall% | Athens, Ga. | L, 4-3
Recap | Stats |
| Fri | 02/16/2001 | Charleston Southern% | Athens, Ga. | W, 6-0
Recap | Stats |
| Sat | 02/17/2001 | Lipscomb% | Athens, Ga. | L, 5-3
Recap | Stats |
| Sat | 02/17/2001 | Georgia% | Athens, Ga. | L, 4-2
Recap | Stats |
| Sun | 02/18/2001 | Marshall% | Athens, Ga. | W, 4-2
Recap | Stats |
| Sun | 02/18/2001 | Georgia% | Athens, Ga. | L, 2-0
Recap |
| Tue | 02/20/2001 | JACKSONVILLE STATE (DH) | Birmingham, Ala. | L, 4-1
Recap | Stats |
| Tue | 02/20/2001 | JACKSONVILLE STATE | Birmingham, Ala. | L, 3-0
Stats |
| Sat | 02/24/2001 | ALABAMA A&M (DH) | Birmingham, Ala. | W, 8-0
Recap | Stats |
| Sat | 02/24/2001 | ALABAMA A&M | Birmingham, Ala. | W, 8-0
Stats |
| Thu | 03/01/2001 | OAKLAND (DH) | Birmingham, Ala. | W, 5-1
Recap | Stats |
| Thu | 03/01/2001 | OAKLAND | Birmingham, Ala. | L, 4-1
Stats |
| Fri | 03/02/2001 | Jacksonville State# | Chattanooga, Tenn. | W, 3-1
Recap | Stats |
| Fri | 03/02/2001 | Chattanooga# | Chattanooga, Tenn. | W, 4-3
Recap | Stats |
| Sat | 03/03/2001 | Jacksonville State# | Chattanooga, Tenn. | W, 8-6
Recap | Stats |
| Sat | 03/03/2001 | Notre Dame# | Chattanooga, Tenn. | L, 9-1
Recap | Stats |
| Fri | 03/09/2001 | Samford+ | Birmingham, Ala. | L, 4-3
Stats |
| Fri | 03/09/2001 | Auburn+ | Birmingham, Ala. | L, 6-2
Recap | Stats |
| Fri | 03/09/2001 | Ball State+ | Birmingham, Ala. | L, 6-3
Stats |
| Sat | 03/10/2001 | Alabama A&M+ | Birmingham, Ala. | W, 17-1
Recap | Stats |
| Sat | 03/10/2001 | Austin Peay+ | Birmingham, Ala. | W, 7-1
Stats |
| Sun | 03/11/2001 | Ball State+ | Pelham, Ala. | L, 9-3
Recap | Stats |
| Thu | 03/15/2001 | Northern Illinois^ | Tampa, Fla. | W, 3-2
Recap | Stats |
| Thu | 03/15/2001 | Fordham^ | Tampa, Fla. | W, 10-2
Recap | Stats |
| Fri | 03/16/2001 | Colgate^ | Tampa, Fla. | W, 2-1
Recap | Stats |
| Fri | 03/16/2001 | Texas A&M^ | Tampa, Fla. | Recap | Stats |
| Sat | 03/17/2001 | Colgate^ | Clearwater, Fla. | W, 2-0
Recap | Stats |
| Sat | 03/17/2001 | South Florida^ | Clearwater, Fla. | L, 5-3
Recap | Stats |
| Sat | 03/24/2001 | SOUTHERN MISS* (DH) | Birmingham, Ala. | L, 10-0
Recap | Stats |
| Sat | 03/24/2001 | SOUTHERN MISS* | Birmingham, Ala. | W, 4-2
Stats |
| Sun | 03/25/2001 | SOUTHERN MISS* | Birmingham, Ala. | L, 6-1
Recap | Stats |
| Tue | 03/27/2001 | GEORGIA STATE (DH) | Birmingham, Ala. | L, 3-0
Recap | Stats |
| Tue | 03/27/2001 | Georgia State | Birmingham, Ala. | L, 3-1
Stats |
| Sat | 03/31/2001 | South Florida* (DH) | Tampa, Fla. | L, 1-0
Recap | Stats |
| Sat | 03/31/2001 | South Florida* | Tampa, Fla. | W, 1-0
Stats |
| Sun | 04/01/2001 | South Florida* | Tampa, Fla. | W, 1-0
Recap | Stats |
| Tue | 04/03/2001 | ALABAMA | Birmingham, Ala. | NTS, Rained Out
|
| Wed | 04/04/2001 | Alabama | Tuscaloosa, Ala. | NTS, Rained Out
|
| Sat | 04/07/2001 | DE PAUL* (DH) | Birmingham, Ala. | L, 3-0
Recap | Stats |
| Sat | 04/07/2001 | DE PAUL* | Birmingham, Ala. | L, 9-0
Stats |
| Sun | 04/08/2001 | DE PAUL* | Birmingham, Ala. | L, 5-0
Recap | Stats |
| Wed | 04/11/2001 | Middle Tennessee (DH) | Murfreesboro, Tenn. | L, 8-0
Recap | Stats |
| Wed | 04/11/2001 | Middle Tennessee | Mufreesboro, Tenn. | L, 2-1
Recap | Stats |
| Fri | 04/13/2001 | Saint Louis* (DH) | St. Louis, Mo. | W, 5-1
Stats |
| Fri | 04/13/2001 | Saint Louis* | St. Louis, Mo. | W, 1-0
Recap | Stats |
| Sat | 04/14/2001 | Saint Louis* | St. Louis, Mo. | W, 4-2
Recap | Stats |
| Sun | 04/15/2001 | FLORIDA STATE (DH) | Birmingham, Ala. | NTS, Rained out
|
| Sun | 04/15/2001 | FLORIDA STATE | Birmingham, Ala. | NTS, Rained Out
|
| Sat | 04/21/2001 | Louisville* (DH) | Louisville, Ky. | L, 3-1
Recap | Stats |
| Sat | 04/21/2001 | Louisville* | Louisville, Ky. | L, 7-6
Stats |
| Sun | 04/22/2001 | Louisville* | Louisville, Ky. | L, 4-2
Recap | Stats |
| Thu | 04/26/2001 | Jacksonville State (DH) | Jacksonville, Ala. | L, 3-0
Recap | Stats |
| Thu | 04/26/2001 | Jacksonville State | Jacksonville, Ala. | L, 6-0
Stats |
| Sat | 04/28/2001 | CHARLOTTE* (DH) | Birmingham, Ala. | W, 4-0
Recap | Stats |
| Sat | 04/28/2001 | CHARLOTTE* | Birmingham, Ala. | W, 5-3
Stats |
| Sun | 04/29/2001 | CHARLOTTE* | Birmingham, Ala. | W, 7-1
Recap | Stats |
| Sat | 05/05/2001 | Houston* (DH) | Houston | W, 6-4
Recap | Stats |
| Sat | 05/05/2001 | Houston* | Houston, Texas | L, 3-0
Stats |
| Sun | 05/06/2001 | Houston* | Houston | L, 2-0
Recap | Stats |
| Thu | 05/10/2001 | South Florida$ | Louisville, Ky. | L, 5-0
Recap | Stats |
| Thu | 05/10/2001 | Saint Louis$ | Louisville, Ky. | W, 2-1
Recap | Stats |
| Fri | 05/11/2001 | South Florida$ | Louisville, Ky. | L, 6-2
Recap | Stats |
All Home Games played on Field #6 at George Ward Park.
* - C-USA Games
# Frost Cutlery Tournament
+ Samford University Invitational Tournament
^ USF/Clearwater Parks and Recreation Tournament.
% Dawg Pound Classic
$ C-USA Tournament
All Times Local
